The FDA issued a warning Thursday against taking diphenhydramine (Benadryl) at more than recommended doses, following accounts of at least one teen dying from overuse.

The agency is investigating reports of teens who have been hospitalized and died after taking part in the latest social media craze encouraging youth to consume a dangerous amount of antihistamine tablets. Cook Children's hospital in Fort Worth, Texas, reported that three teens were hospitalized in May after taking up to 14 tablets. One 15-year-old girl on Oklahoma died from an overdose in August spurred by the challenge.

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